13945 IUPAC Gold Book - stealth 10.1351/goldbook.13945 13945 current synonym: stealth biomedical polymer 1 Qualifier for a macromolecule, a surface, or a device that is not detected by defense proteins of the complement and the Mononuclear Phagocyte System, especially macrophages, after introduction in parental compartments. Detection by natural defenses generally leads to the destruction of the device or of the surrounding tissues. Surfaces are often decorated by chemical entities aimed at suppressing the activation of the natural defense processes. PAC, 2012, 84, 377. 'Terminology for biorelated polymers and applications (IUPAC Recommendations 2012)' on page 402 (https://doi.org/10.1351/PAC-REC-10-12-04) https://goldbook.iupac.org/terms/view/13945/html https://goldbook.iupac.org/terms/view/13945/json https://goldbook.iupac.org/terms/view/13945/plain Citation: 'stealth' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13945 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-06-04T15:55:21+00:00