Title: solid dispersion
Long Title: IUPAC Gold Book - solid dispersion
DOI: 10.1351/goldbook.13917
Status: current

Definition
Solid multiphasic mixture with at least one polymer component dominating.

Notes
1) The nonpolymeric components can act as fillers.
2) The dispersed compounds can be in clusters of particles.
3) Solid dispersion is commonly prepared by three different methods, namely, solventbased, fusion-melt, and hybrid fusion-solvent methods.
4) In pharmaceutical preparations, incompatible polymer-drug mixtures are generally solid dispersions.

Source
- PAC, 2012, 84, 377. 'Terminology for biorelated polymers and applications (IUPAC Recommendations 2012)' on page 395 (https://doi.org/10.1351/PAC-REC-10-12-04)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13917/html
- json: https://goldbook.iupac.org/terms/view/13917/json
- xml: https://goldbook.iupac.org/terms/view/13917/xml

Citation: Citation: 'solid dispersion' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13917
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Accessed: 2026-06-04T20:39:43+00:00