13687 IUPAC Gold Book - somatic diversification theory 10.1351/goldbook.13687 13687 current 1 Theory that very few immunoglobulins (Ig) are inherited, but that extensive antibody diversity arises from mutations in non-reproductive cells. V(D)J recombination https://goldbook.iupac.org//terms/view/13770 somatic recombination https://goldbook.iupac.org//terms/view/13689 PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1246 (https://doi.org/10.1351/PAC-REC-11-06-03) https://goldbook.iupac.org/terms/view/13687/html https://goldbook.iupac.org/terms/view/13687/json https://goldbook.iupac.org/terms/view/13687/plain Citation: 'somatic diversification theory' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13687 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-04-18T00:19:19+00:00