Title: Sjögren syndrome
Long Title: IUPAC Gold Book - Sjögren syndrome
DOI: 10.1351/goldbook.13680
Status: current

Definition
Chronic inflammation of the lachrymal and salivary glands, often accompanied by rheumatoid arthritis (RA) and the presence of autoantibodies in the blood, occurring chiefly among women.

Note
Two types of Sjögren syndrome are distinguished: a primary (isolated) type and a secondary type associated with another underlying autoimmune disease [e.g., RA, systemic lupus erythematosus (SLE), systemic sclerosis (SSc), primary biliary cirrhosis (PBC), autoimmune hepatitis (AIH), multiple sclerosis, autoimmune thyroiditis, etc.]. Ro/SS-A and La/SS-B autoantibodies are used as classification criteria.

Related Terms
- autoantibodies: https://goldbook.iupac.org//terms/view/12913
- autoimmune hepatitis (AIH): https://goldbook.iupac.org//terms/view/12921
- autoimmune thyroiditis: https://goldbook.iupac.org//terms/view/13741
- primary biliary cirrhosis (PBC): https://goldbook.iupac.org//terms/view/13600
- rheumatoid arthritis (RA): https://goldbook.iupac.org//terms/view/13651
- systemic lupus erythematosus (SLE): https://goldbook.iupac.org//terms/view/13710

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1245 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13680/html
- json: https://goldbook.iupac.org/terms/view/13680/json
- xml: https://goldbook.iupac.org/terms/view/13680/xml

Citation: Citation: 'Sjögren syndrome' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13680
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Accessed: 2026-07-14T00:39:13+00:00