Title: respiratory burst
Long Title: IUPAC Gold Book - respiratory burst
DOI: 10.1351/goldbook.13646
Status: current

Definition
Generation of cytotoxic superoxide from dioxygen due to increased NADPH oxidase activity, typically occurring in activated neutrophils.

Related Terms
- cytotoxic: https://goldbook.iupac.org//terms/view/13071
- neutrophil activation: https://goldbook.iupac.org//terms/view/13511
- neutrophils: https://goldbook.iupac.org//terms/view/13510

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1240 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13646/html
- json: https://goldbook.iupac.org/terms/view/13646/json
- xml: https://goldbook.iupac.org/terms/view/13646/xml

Citation: Citation: 'respiratory burst' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13646
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-08T04:49:58+00:00