prozone effect

https://doi.org/10.1351/goldbook.13620
Loss of immunoprecipitation or agglutination that occurs when antibody concentration is increased to an extent that the antibody is in such excess that it is no longer able to effectively cross-link the antigen. A similar phenomenon may occur in antigen excess.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1237 [Terms] [Paper]
Citation: 'prozone effect' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13620 RIS BibTex EndNote
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