Title: passive cutaneous anaphylaxis test
Long Title: IUPAC Gold Book - passive cutaneous anaphylaxis test
DOI: 10.1351/goldbook.13538
Status: current

Definition
Assay for allergenicity in which an antibody is injected intradermally into a test animal followed at a later time (anywhere from \(\pu{3}\) to \(\pu{48 h}\)) with an intravenous injection of a mixture of a test antigen and a dye (typically Evans blue). Increased vascular permeability at the site of antigen-antibody reaction is visualized by extravasation of the dye.

Related Term
- allergenicity: https://goldbook.iupac.org//terms/view/12857

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1225 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13538/html
- json: https://goldbook.iupac.org/terms/view/13538/json
- xml: https://goldbook.iupac.org/terms/view/13538/xml

Citation: Citation: 'passive cutaneous anaphylaxis test' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13538
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Accessed: 2026-08-01T11:15:20+00:00