mast cell activation disorder

initialisms: MCAD, MCAS
synonym: mast cell activation syndrome
https://doi.org/10.1351/goldbook.13443
Disorder or syndrome in which there is evidence of systemic, inappropriate release of mast cell mediators.
Note: While people with MCAD/MCAS have a normal or near-normal tryptase level and a bone marrow biopsy that contains a normal number of mast cells, they experience most of the same symptoms as someone with mastocytosis.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1211 [Terms] [Paper]
Citation: 'mast cell activation disorder' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13443 RIS BibTex EndNote
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