Title: major histocompatibility complex molecule
Long Title: IUPAC Gold Book - major histocompatibility complex molecule
DOI: 10.1351/goldbook.13434
Status: current

Definition
Any of the cell-surface glycoprotein alloantigens encoded by the major histocompatibility complex (MHC) that are involved in the regulation of immune responses and can cause the rejection of grafted tissues, cells, and tumors bearing them.

Related Terms
- alloantigens: https://goldbook.iupac.org//terms/view/12861
- major histocompatibility complex (MHC): https://goldbook.iupac.org//terms/view/13430
- rejection: https://goldbook.iupac.org//terms/view/13645

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13434/html
- json: https://goldbook.iupac.org/terms/view/13434/json
- xml: https://goldbook.iupac.org/terms/view/13434/xml

Citation: Citation: 'major histocompatibility complex molecule' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13434
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Accessed: 2026-07-13T23:13:03+00:00