13433 IUPAC Gold Book - major histocompatibility complex class III molecule 10.1351/goldbook.13433 13433 current synonyms: class III MHC gene product, MHC class III molecule 1 Antigen encoded by the major histocompatibility complex (MHC) including several complement factors, tumor necrosis factor (TNF) $\ce{\upalpha\!}$, and lymphotoxin. The genes are found on the short arm of chromosome 6 between class I and class II genes, and although the gene products share no common function with the major histocompatibility complex (MHC) class I and MHC class II molecules, they are often discussed together. MHC class II molecules https://goldbook.iupac.org//terms/view/13432 lymphotoxin https://goldbook.iupac.org//terms/view/13421 major histocompatibility complex (MHC) https://goldbook.iupac.org//terms/view/13430 major histocompatibility complex (MHC) class I https://goldbook.iupac.org//terms/view/13431 tumor necrosis factor (TNF) https://goldbook.iupac.org//terms/view/13762 PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03) https://goldbook.iupac.org/terms/view/13433/html https://goldbook.iupac.org/terms/view/13433/json https://goldbook.iupac.org/terms/view/13433/plain Citation: 'major histocompatibility complex class III molecule' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13433 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-14T00:45:15+00:00