Forssman antigen

https://doi.org/10.1351/goldbook.13158
Glycolipid heterophile antigen (globopentosylceramide) expressed on cell surfaces during embryonic and adult life in rodents and other mammals, and found in many pathogens, but probably not in humans.
Notes:
  1. Anti-Forssman antibodies directed against the terminal sugar moiety are commonly found in plasma and may be involved in Guillain–Barré syndrome (GBS).
  2. Anti-Forssman antibodies reportedly disrupt tight junction formation, apical-basal polarization, and cell adhesion.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1167 [Terms] [Paper]
Citation: 'Forssman antigen' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13158 RIS BibTex EndNote
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