first line of defence

https://doi.org/10.1351/goldbook.13151
Surface tissues, notably the skin, respiratory tract, and gastrointestinal tract.
Notes:
  1. These tissues are rich in immunocompetent cells that form a first line of defense by recognizing pathogens, destroying them with secretory antibodies, or preventing their intrusion into the organism.
  2. Internal organs may also have a first line of defense, e.g., the microglia have been considered as a first line of defense against brain infections.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1166 [Terms] [Paper]
Citation: 'first line of defence' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13151 RIS BibTex EndNote
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