Title: cluster of differentiation antigen
Long Title: IUPAC Gold Book - cluster of differentiation antigen
DOI: 10.1351/goldbook.13018
Status: current

Definition
Any of a family of molecular markers on cell surfaces that may be used operationally to define phenotype, origin, and activation state of the cell.

Note
The CD antigens expressed by a T cell vary with its stage of development and thus with its role in the immune response.

Related Terms
- T cell: https://goldbook.iupac.org//terms/view/13724
- activation: https://goldbook.iupac.org//terms/view/13401

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1145 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13018/html
- json: https://goldbook.iupac.org/terms/view/13018/json
- xml: https://goldbook.iupac.org/terms/view/13018/xml

Citation: Citation: 'cluster of differentiation antigen' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13018
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Accessed: 2026-08-01T10:06:49+00:00