chronic granulomatous disease

https://doi.org/10.1351/goldbook.13006
Immunodeficiency disease in which multiple granulomas form as a result of defective elimination of bacteria by phagocytes.
Note: It is caused by deficiency of the NADPH oxidase system of enzymes that generates superoxide involved in bacterial killing.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1143 [Terms] [Paper]