Member of the Bcl protein family that protects cells from apoptosis by binding to the mitochondrial membrane.
Note: It is encoded by the bcl-2 gene, which was discovered at the breakpoint of an oncogenic chromosomal translocation in
B-cell leukemia.
Source: PAC, 2012,
84, 1113. (
IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1134 [
Terms] [
Paper]