Title: Arthus reaction
Long Title: IUPAC Gold Book - Arthus reaction
DOI: 10.1351/goldbook.12904
Status: current

Definition
Local antibody-mediated hypersensitivity reaction in which antigen-antibody complexes which fix complement are deposited in the walls of small vessels, often in the skin, causing acute inflammation with an infiltration of neutrophils.

Related Terms
- Gell and Coombs classification: https://goldbook.iupac.org//terms/view/13167
- hypersensitivity: https://goldbook.iupac.org//terms/view/13241
- neutrophils: https://goldbook.iupac.org//terms/view/13510

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1128 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12904/html
- json: https://goldbook.iupac.org/terms/view/12904/json
- xml: https://goldbook.iupac.org/terms/view/12904/xml

Citation: Citation: 'Arthus reaction' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12904
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-07-14T08:23:11+00:00