<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>12899</id>
  <title>antiphospholipid syndrome</title>
  <longtitle>IUPAC Gold Book - antiphospholipid syndrome</longtitle>
  <doi>10.1351/goldbook.12899</doi>
  <code>12899</code>
  <status>current</status>
  <initialism><em>initialism</em>: APS</initialism>
  <definitions>
    <item>
      <id>1</id>
      <text>One of the most common autoimmune diseases, characterized by thrombosis, recurrent spontaneous abortions, and the presence of antiphospholipid antibodies.</text>
      <notes>
        <item>Antiphospholipid syndrome may occur as an isolated disease (primary APS) or in combination with another autoimmune disease, especially systemic lupus erythematosus (SLE) (secondary APS).</item>
      </notes>
      <links>
        <item>
          <term>autoimmune diseases</term>
          <url>https://goldbook.iupac.org//terms/view/12919</url>
        </item>
        <item>
          <term>systemic lupus erythematosus (SLE)</term>
          <url>https://goldbook.iupac.org//terms/view/13710</url>
        </item>
      </links>
      <sources>
        <item>PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1127 (https://doi.org/10.1351/PAC-REC-11-06-03)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/12899/html</html>
    <json>https://goldbook.iupac.org/terms/view/12899/json</json>
    <plain>https://goldbook.iupac.org/terms/view/12899/plain</plain>
  </altoutputs>
  <citation>Citation: 'antiphospholipid syndrome' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12899</citation>
  <license>The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.</license>
  <collection>If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .</collection>
  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-07-14T02:15:51+00:00</accessed>
</term>
