scaffold hopping

https://doi.org/10.1351/goldbook.12725
Exchange of one scaffold for another while maintaining molecular features that are important for biological properties.
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1750 [Terms] [Paper]
Citation: 'scaffold hopping' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.12725 RIS BibTex EndNote
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