12687 IUPAC Gold Book - multitarget-directed ligand 10.1351/goldbook.12687 12687 current initialism: MTDL synonym: multitarget drug 1 Ligand acting on more than one distinct molecular target. Targets may be of the same or different mechanistic classes. molecular target https://goldbook.iupac.org//terms/view/12684 PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1742 (https://doi.org/10.1351/PAC-REC-12-11-23) https://goldbook.iupac.org/terms/view/12687/html https://goldbook.iupac.org/terms/view/12687/json https://goldbook.iupac.org/terms/view/12687/plain Citation: 'multitarget-directed ligand' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12687 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-04-18T19:01:45+00:00