Title: multitarget-directed ligand
Long Title: IUPAC Gold Book - multitarget-directed ligand
DOI: 10.1351/goldbook.12687
Status: current

Definition
Ligand acting on more than one distinct molecular target. Targets may be of the same or different mechanistic classes.

Related Term
- molecular target: https://goldbook.iupac.org//terms/view/12684

Source
- PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1742 (https://doi.org/10.1351/PAC-REC-12-11-23)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12687/html
- json: https://goldbook.iupac.org/terms/view/12687/json
- xml: https://goldbook.iupac.org/terms/view/12687/xml

Citation: Citation: 'multitarget-directed ligand' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12687
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-04-18T19:01:46+00:00