multiparameter optimisation

initialism: MPO
https://doi.org/10.1351/goldbook.12686
Drug-likeness penetrability algorithm derived from CLOGP, clogD, molar mass, topological polar surface area, number of hydrogen-bond donors, and \(\pu{p}K_{\rm{a}}\).
Note: The MPO desirability score is larger or equal to 4 on a scale of 0 to 6.
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1742 [Terms] [Paper]
Citation: 'multiparameter optimisation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.12686 RIS BibTex EndNote
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