frequent hitter

https://doi.org/10.1351/goldbook.12661
Structural feature that regularly results in a positive response in a variety of high-throughput or primary screens.
Note: Such compounds often exert their actions through nonspecific mechanisms and are therefore unreliable leads.
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1735 [Terms] [Paper]
Citation: 'frequent hitter' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.12661 RIS BibTex EndNote
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