surface-enhanced laser desorption/ionization

acronym: SELDI
https://doi.org/10.1351/goldbook.12586
Variant of matrix-assisted laser desorption/ionization (MALDI) in which the matrix is replaced by a surface coating of a chromatographic stationary phase designed to selectively retain different subsets of proteins or peptides from a mixture depending on their physico-chemical properties or biochemical affinity characteristics.
Note: Originally this technique was named surface-enhanced affinity capture (SEAC) to distinguish it from surface-enhanced neat desorption (SEND) where the surface coating is designed to increase the efficiency of laser desorption.
Source:
PAC, 2013, 85, 1515. (Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)) on page 1593 [Terms] [Paper]
Citation: 'surface-enhanced laser desorption/ionization' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.12586 RIS BibTex EndNote
TextXMLJSON