12479 IUPAC Gold Book - mass discrimination 10.1351/goldbook.12479 12479 current 1 Differences in overall detection sensitivities for ions of different m/z values in a mass spectrum, caused by variations in ionization efficiency, transmission efficiency through the interface between the ion source and the analyzer vacuum system, analyzer, and detector response. transmission efficiency https://goldbook.iupac.org//terms/view/12601 PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1563 (https://doi.org/10.1351/PAC-REC-06-04-06) https://goldbook.iupac.org/terms/view/12479/html https://goldbook.iupac.org/terms/view/12479/json https://goldbook.iupac.org/terms/view/12479/plain Citation: 'mass discrimination' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12479 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-06-20T04:03:17+00:00