Title: treadmill test
Long Title: IUPAC Gold Book - treadmill test
DOI: 10.1351/goldbook.12148
Status: current

Definition
Procedure used to assess limb function and strength, often to evaluate models of peripheral neuropathy, in which a rodent is placed in an enclosed lane upon a surface that can be made to move at variable speed in a retrograde manner, thus allowing observation of the animal’s gait dimension during sustained attempt at forward motion.

Notes
1) The test can be modified to provide a test of endurance in the animal, or to test motor coordination and gait.
2) A treadmill test with humans is commonly used in a medical setting for assessment of cardiac performance and pulmonary function.

Related Term
- motor coordination: https://goldbook.iupac.org//terms/view/11884

Source
- PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 913 (https://doi.org/10.1515/pac-2015-0103)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12148/html
- json: https://goldbook.iupac.org/terms/view/12148/json
- xml: https://goldbook.iupac.org/terms/view/12148/xml

Citation: Citation: 'treadmill test' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12148
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-08-04T04:07:37+00:00