12144 IUPAC Gold Book - tranquilizer 10.1351/goldbook.12144 12144 current 1 Drug that calms and pacifies with minimal sedating or depressant effects. A tranquilizer decreases anxiety (i.e., has anxiolytic properties) or agitation without necessarily decreasing awareness or wakefulness. Tranquilizers at higher dose may induce sleep. Minor tranquilizers are sedatives, examples of which include benzodiazepines, antihistamines, alcohol, cannabis, and chloral hydrate. Major tranquilizers include antipsychotic drugs and neuroleptics. antipsychotic https://goldbook.iupac.org//terms/view/11596 anxiolytic https://goldbook.iupac.org//terms/view/11598 neuroleptics https://goldbook.iupac.org//terms/view/11937 sedating https://goldbook.iupac.org//terms/view/12067 PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 913 (https://doi.org/10.1515/pac-2015-0103) https://goldbook.iupac.org/terms/view/12144/html https://goldbook.iupac.org/terms/view/12144/json https://goldbook.iupac.org/terms/view/12144/plain Citation: 'tranquilizer' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12144 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-26T02:33:44+00:00