{"term":{"id":"11539","title":"controlled release","longtitle":"IUPAC Gold Book - controlled release","doi":"10.1351\/goldbook.11539","code":"11539","status":"current","definitions":[{"id":1,"text":"Detection principle for a chemically modified electrode (CME) in which an analyte or reagent accumulated at a CME undergoes quantitative release (egress, stripping, expulsion, or microdosing) to the test solution, under electrochemical or chemical control.","notes":{"1":"Different mechanisms are involved in controlled release from the CME depending on the nature of the analyte or reagent and the method of accumulation. In the case of accumulation by covalent bonding, the anchoring bond is cleaved (ruptured) electrochemically. In the case of ion-exchange accumulation, an ionic (redox or acid-base) analyte or reagent is released by neutralizing its charge or the charge of the ion-exchanging redox polymer film or conducting polymer film."},"sources":["PAC, 2020, 92, 641. 'Terminology of Electrochemical Methods of Analysis (IUPAC Recommendations 2019)' on page 658 (https:\/\/doi.org\/10.1515\/pac-2018-0109)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/11539\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/11539\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/11539\/plain"},"citation":"Citation: 'controlled release' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.11539","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-07-24T12:33:43+00:00"}}