The conditional probability that is assigned to a quantity before relevant evidence is taken into account, for example, the prior probability of an active
compound would be the fraction of the compounds in the dataset that are active.
Source:
PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 253 (https://doi.org/10.1515/pac-2012-1204)