The influence of an observation on the coefficients of a fitted equation.
Note: An observation with high leverage may be an outlier or in poorly explored property space.
Source:
PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 249 (https://doi.org/10.1515/pac-2012-1204)