A 3D-QSAR method similar to CoMFA that instead uses Gaussian-type functions to calculate the 3D properties of the molecules by the similarity of each molecule to each probe at each lattice position surrounding the molecules.
Source: PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 244 (https://doi.org/10.1515/pac-2012-1204)