https://doi.org/10.1351/goldbook.11384
Family of genes important in development, the proteins they encode, or the signal transduction pathways they determine.
Notes:
- Wnt pathways are involved throughout embryonic development, regulating such processes as cytoskeletal dynamics, cell polarity, proliferation, migration, and body axis patterning.
- The proteins signal by binding to cell-surface G-protein coupled receptors of the Frizzled family that signal to members of the Dishevelled (Dsh) family of cytoplasmic phosphoproteins.
- Wnt is derived from Wingless-related integration site, originally identified in Drosophila.