Procedure in which immature female rodents are treated for three days with a test substance. A resultant increase in uterine wet weight suggests an estrogenic activity of the substance.
Source: PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 818 (https://doi.org/10.1515/pac-2015-1202)