trisomy 21

synonym: Down syndrome
https://doi.org/10.1351/goldbook.11325
Presence of an extra chromosome 21.
Notes:
  1. This produces a characteristic constellation of physical abnormalities with delayed growth and mental development, but is compatible with life into adulthood.
  2. The formerly used terms mongoloid and mongolism are now considered offensive.
Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 815 [Terms] [Paper]
Citation: 'trisomy 21' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.11325 RIS BibTex EndNote
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