{"term":{"id":"11319","title":"triple screen","longtitle":"IUPAC Gold Book - triple screen","doi":"10.1351\/goldbook.11319","code":"11319","status":"current","synonym":"<em>synonym<\/em>: triple test","definitions":[{"id":1,"text":"Measurement of maternal serum levels of alpha-fetoprotein, human chorionic gonadotropin, and estriol, usually in the second trimester of pregnancy, that can serve as an indicator of risk for certain fetal chromosomal abnormalities and neural tube defects.","links":[{"term":"alpha-fetoprotein","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/10358"},{"term":"chromosomal abnormalities","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/10524"},{"term":"estriol","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/10679"},{"term":"fetal","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/10718"},{"term":"human chorionic gonadotropin","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/10517"},{"term":"neural tube defects","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/11004"},{"term":"pregnancy","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/11116"},{"term":"trimester","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/11318"}],"sources":["PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 815 (https:\/\/doi.org\/10.1515\/pac-2015-1202)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/11319\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/11319\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/11319\/plain"},"citation":"Citation: 'triple screen' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.11319","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-07-14T16:40:44+00:00"}}