testicular feminization

https://doi.org/10.1351/goldbook.11294

Type of male pseudohermaphroditism in which the individual has a male karyotype and testes present within the abdominal cavity, but develops external female genitalia and female secondary sexual characteristics.

Notes:
  1. Testicular feminization is due to an androgen receptormutation, causing the target tissues to be insensitive to the masculinizing effects of androgens.
  2. Clinical presentation is usually as a phenotypic female with primary amenorrhea.
Source:
PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 812 (https://doi.org/10.1515/pac-2015-1202)