retinoic acid

synonym: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
https://doi.org/10.1351/goldbook.11180
Acidic metabolite of vitamin A.
Notes:
  1. Retinoic acid binds to the retinoic acid receptor (RAR), which then acts as a transcription factor.
  2. The role of RAR in development (e.g., in regulating homeobox genes) accounts for the teratogenicity of related pharmaceuticals.
Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 800 [Terms] [Paper]
Citation: 'retinoic acid' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.11180 RIS BibTex EndNote
Div. VIITextXMLJSON