https://doi.org/10.1351/goldbook.11165
Process in tissue or organ development in which epithelium induces changes in the mesenchyme and the mesenchyme also induces changes in the epithelium, through paracrine signaling.
Note: An example occurs during development of the prostate, in which mesenchyme of the urogenital sinus influences differentiation and patterning of the prostatic epithelium, and the developing epithelium induces prostatic mesenchymal cells to differentiate into smooth muscle and other prostatic stromal cells.