Congenital disorder of keratinization, characterized by dryness and scaling of the skin, often associated with other defects and with abnormalities of lipid metabolism.
Source:
PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 767 (https://doi.org/10.1515/pac-2015-1202)