holoprosencephaly

synonym: arhinencephaly
https://doi.org/10.1351/goldbook.10803

Birth defect in which the embryonic forebrain fails to divide completely to form the cerebral hemispheres.

Note: This results in varying degrees of mental impairment and abnormal development of eye, nose, and lip.
Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 764 [Terms] [Paper]