Procedure in which mutations induced by an agent are studied in germ line cells or somatic stem cells from a transgenic animal (rodent), containing reporter genes for detection of various mutations.
Source: PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 760 (https://doi.org/10.1515/pac-2015-1202)