Procedure in which sexually mature male and spawning female fish are exposed to a test substance and multiple endpoints, including egg production, endocrine activity, vitellogenin, and gonadal histopathology are measured.
Source: PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 756 (https://doi.org/10.1515/pac-2015-1202)