Detoxification enzyme (EC 3.3.2.9), located mainly in the endoplasmic reticulum, that hydrolyzes epoxides, converting them to metabolites that can be more rapidly excreted.
Source: PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 751 [Terms] [Paper]