Title: decidual cell response technique
Long Title: IUPAC Gold Book - decidual cell response technique
DOI: 10.1351/goldbook.10589
Status: current

Definition
Biological test method in which pseudopregnant rats undergo a surgical treatment of the uterus to induce uterine differentiation and proliferation, resulting in massive tissue growth that mimics the response of the uterus during normal blastocyst implantation.

Note
Measurement of decidual growth during chemical treatment can be used to assess both hormonal status and uterine function. Uterine weight is a sensitive measure of the success of the decidual cell response.

Related Terms
- blastocyst: https://goldbook.iupac.org//terms/view/10462
- decidual: https://goldbook.iupac.org//terms/view/10587
- decidual cell: https://goldbook.iupac.org//terms/view/10588
- hormonal: https://goldbook.iupac.org//terms/view/10810
- implantation: https://goldbook.iupac.org//terms/view/10841
- pseudopregnant: https://goldbook.iupac.org//terms/view/11150
- uterus: https://goldbook.iupac.org//terms/view/11350

Source
- PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 742 (https://doi.org/10.1515/pac-2015-1202)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/10589/html
- json: https://goldbook.iupac.org/terms/view/10589/json
- xml: https://goldbook.iupac.org/terms/view/10589/xml

Citation: Citation: 'decidual cell response technique' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10589
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .
Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-07-21T22:43:28+00:00