Cre/loxP

https://doi.org/10.1351/goldbook.10570
Bacterial system in which the Cre protein mediates DNA recombination between specific DNA sequences known as lox-P sites.
Note: This system is used in mammalian cells to delete (or invert) a stretch of DNA by flanking it with lox-P sites and then exposing the cell to Cre protein at some predetermined time.
Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 740 [Terms] [Paper]
Citation: 'Cre/loxP' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.10570 RIS BibTex EndNote
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