10508 IUPAC Gold Book - checkpoint pathway 10.1351/goldbook.10508 10508 current 1 Type of pathway used in intracellular signaling, activated in response to a cell’s own internal imbalance or to errors in its synthetic activities. Activation of checkpoint pathways leads to a delay in certain synthetic processes until other processes are complete, thereby averting damage. PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 734 (https://doi.org/10.1515/pac-2015-1202) https://goldbook.iupac.org/terms/view/10508/html https://goldbook.iupac.org/terms/view/10508/json https://goldbook.iupac.org/terms/view/10508/plain Citation: 'checkpoint pathway' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10508 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-28T10:30:08+00:00