Type of pathway used in intracellular signaling, activated in response to a cell’s own internal imbalance or to errors in its synthetic activities.
Note: Activation of checkpoint pathways leads to a delay in certain synthetic processes until other processes are complete, thereby averting damage.
Source:
PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 734 (https://doi.org/10.1515/pac-2015-1202)