{"term":{"id":"10466","title":"blood–testis barrier","longtitle":"IUPAC Gold Book - blood–testis barrier","doi":"10.1351\/goldbook.10466","code":"10466","status":"current","synonym":"<em>synonyms<\/em>: blood-seminiferous tubule barrier, Sertoli cell barrier (SCB)","definitions":[{"id":1,"text":"Occluding barrier, formed by the Sertoli cells of the seminiferous tubules, that separates the more mature cells of spermatogenesis from blood-borne products.","notes":{"1":"The name \"blood-testis barrier\" is misleading in that it is not a blood-organ barrier in a strict sense, but is formed between Sertoli cells of the seminiferous tubule and, as such, isolates the further developed stages of germ cells from the blood. A more correct term is the \"Sertoli cell barrier\" (SCB)."},"links":[{"term":"Sertoli cells","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/11208"},{"term":"germ cells","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/10762"},{"term":"seminiferous tubules","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/11204"},{"term":"spermatogenesis","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/11240"}],"sources":["PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 730 (https:\/\/doi.org\/10.1515\/pac-2015-1202)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/10466\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/10466\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/10466\/plain"},"citation":"Citation: 'blood–testis barrier' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.10466","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-07-12T09:55:10+00:00"}}