Ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons.
Notes: - This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as various forms of cytochrome P450 family 1 members.
- It also appears to play a role in cell proliferation and differentiation during vertebrate development, including hematopoiesis and development of the lymphoid and immune systems.
Source:
PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 727 (https://doi.org/10.1515/pac-2015-1202)