Abnormal enlargement of the hands, feet, and face in adults, caused by overproduction of growth hormone by the pituitary gland.
Source:
PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 716 (https://doi.org/10.1515/pac-2015-1202)