https://doi.org/10.1351/goldbook.10271
Immersion solid-phase microextraction where the extraction phase is designed to minimize sorption of particles or macromolecules present in the sample matrix.
Note: Sorption of particles and macromolecules by the extraction phase is a potential source of interference in the extraction process or subsequent determination of analytes when sampling occurs by direct contact of the extraction phase with the sample. In some cases this can be addressed by incorporation of specific properties in the extraction phase that minimize matrix-extraction phase interactions for problem matrix components.